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New Drugs for Trigeminal Neuralgia

  • Writer: Olle Corneliuson
    Olle Corneliuson
  • 3 days ago
  • 1 min read

The development of new drugs that may be of value in the treatment of trigeminal neuralgia is reviewed in a recent article emanating from the Mayo Clinic. Of primary interest are lacosamide and eslicarbazepine.

One study found that 66% of patients who had failed first-line medical therapies had improvement on lacosamide with 34% reporting complete pain relief. Adverse effects were dizziness, sleepiness and instability.

Eslicarbazepine, a cousin to carbamazepine and oxcarbazepine, showed at least 50% reduction in pain from baseline in a small study comprising 12 patients. Side effects were dizziness and hyponatremia.


Curr Opin Neurol. 2026 Apr 9. doi: 10.1097/WCO.0000000000001480. Online ahead of print.

 
 
 

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